Figure 1.

A) Time course of clinical disease in challenged pigs immunized with peptide B (group 1), peptide TB (group2), and in non-immunized pigs (group 3), after challenge with FMDV C-S8c1. The mean body temperature (°C) [right, rhombs] and the score of the clinical signs (grey curve; calculated as indicated in Materials and Methods) are shown. B) Box plot showing the range of the maximum clinical scores (see Materials and Methods) recorded for the individual animals from groups 1, 2 and 3 after challenge. Statistically significant differences were found in the median values (line into the box) between groups 2 and 1 (* P = 0.026) and 2 and 3 (** P = 0.003).

Cubillos et al. Virology Journal 2012 9:66   doi:10.1186/1743-422X-9-66
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