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Open Access Highly Accessed Review

Rabies molecular virology, diagnosis, prevention and treatment

Muhammad Zubair Yousaf15*, Muhammad Qasim2, Sadia Zia3, Muti ur Rehman Khan4, Usman Ali Ashfaq2 and Sanaullah Khan1

Author Affiliations

1 Molecular Parasitology and Virology Laboratory, Department of Zoology, Kohat University of Science and Technology, Kohat, Pakistan

2 Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan

3 Department of Biological Sciences, Forman Christian College, Ferozpur road, Lahore, Pakistan

4 Department of Pathology, University of Veterinary and Animal Sciences, Lahore, Pakistan

5 Department of Zoology, Kohat University of Science and Technology, Kohat, Khyber Pakhtunkhwa, Pakistan

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Virology Journal 2012, 9:50  doi:10.1186/1743-422X-9-50

Published: 21 February 2012

Abstract

Rabies is an avertable viral disease caused by the rabid animal to the warm blooded animals (zoonotic) especially human. Rabies occurs in more than 150 countries and territories. According to an estimation by WHO, almost 55,000 people die because of rabies every year. The Dogs are the major reason behind this, approximately 99% human deaths caused by dog's bites. Developing and under developing countries, both are the victims of rabies. With the post-exposure preventive regimes, 327,000 people can prevent this disease annually.

The current article mainly covers the genome, virology, symptoms, epidemiology, diagnostic methods, and the high risk countries around the globe.

Keywords:
Rabies; Zoonosis; Vaccine; Prevention