Table 4

Various antigenically important amino acid/motifs/deletions observed in different gene segments of Pakistani H5N1 viruses
HPAI AA Motif HA 222 HA 224

NA Deletion

49-68

NA 275 MP 26 MP 27 MP 30 MP 31 MP 34 NS Deletion 80-84 NS 149 PDZ Binding domain PB2 627
Ck/Rawalakot/2441/06 PQGERRRKKRGLF Q G YES H L V A S G YES A ESKV K
Ck/Sihala/3303/06 PQGERRRKKRGLF Q G YES H L V A S G YES A ESKV K
Ck/Laore/3320/06 PQGERRRKKRGLF Q G YES H L V A S G YES A ESKV K
Gs/Lahore/3321/06 PQGERRRKKRGLF Q G YES H - - - - - - - - -
Pck/Mansehra/7558/07 PQGERRRKKRGLF Q G YES H - - - - - - - - -
Gs/Islamabd/7757/07 PQGERRRKKRGLF Q G YES H - - - - - - - - -
Tk/Islamabad/7871/07 PQGERRRKKRGLF Q G YES H - - - - - - - - -
Tk/Islamabad/7873/07 PQGERRRKKRGLF Q G YES H - - - - - - - - -
Crow/Peshawar/7914/07 PQGERRRKKRGLF Q G YES H - - - - - - - - -
Pck/Chakshahzad/9238/07 PQGERRRKKRGLF Q G YES H - - - - - - - - -
Ck/Mansehra/10337/07 PQGERRRKKRGLF Q G YES H - - - - - - - - -
Ck/Karachi/520/08 PQGERRRKKRGLF Q G YES H - - - - - YES A ESKV -
Ck/Lahore/610/08 PQGERRRKKRGLF Q G YES H - - - - - YES A ESKV -
Ck/Karachi/612/08 PQGERRRKKRGLF Q G YES H - - - - - YES A ESKV -
Crow/Karachi/11672/08 PQGERRRKKRGLF Q G YES H - - - - - YES A ESKV -

Ck: Chicken, Gs: Goose, Ty: Turkey, Cw: Crow, Pk: Peacock, Pak: Pakistan.

Not done/Data not available.

Siddique et al.

Siddique et al. Virology Journal 2012 9:300   doi:10.1186/1743-422X-9-300

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