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Open Access Case Report

Detection of human coronavirus strain HKU1 in a 2 years old girl with asthma exacerbation caused by acute pharyngitis

Razieh Amini1, Fatemeh Jahanshiri2, Yasaman Amini23, Zamberi Sekawi2 and Farid Azizi Jalilian24*

Author Affiliations

1 Department of Molecular Medicine, Faculty of Medicine, Hamadan University of Medical Sciences, HUMS, Hamadan, Iran

2 Department of Medical Microbiology, Faculty of Medicine and Health Sciences, 43400 UPM Serdang, Selangor, Malaysia

3 Department of Infectious Disease, Masih Daneshvari hospital, Tehran, Iran

4 Department of Medical Microbiology, Faculty of Medicine, Ilam University of Medical Sciences, 69316 IUMS, Ilam, Iran

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Virology Journal 2012, 9:142  doi:10.1186/1743-422X-9-142

Published: 3 August 2012


Respiratory viral infections can trigger asthma attack which may lead to sever morbidity. In this report, using molecular methods, we show the chronological association between human coronavirus - HKU1 infection and asthma exacerbation in a two years and seven months old asthmatic girl who was not under treatment and was otherwise healthy.

Respiratory viral infection; Asthma; Coronavirus