Table 2

Antiviral effect of prestimulation with Toll-like receptor specific ligands against influenza A/Puerto Rico/8/34.

TLR ligand

Receptor

Ratio of MLD50 (log10EID50) between LPS-pretreated and mock-treated mice


Synthetic mycoplasmal lipoprotein (FSL-1)

TLR2

1.0

Synthetic analog of dsRNA (Poly(I:C))

TLR3

0.66

LPS from E. coli K12 msbB

TLR4

1.0

LPS from E. coli serotype O111:B4

0.66

Guanosine analog (loxoribine)

TLR7

0.66


Shinya et al. Virology Journal 2011 8:97   doi:10.1186/1743-422X-8-97

Open Data