Table 6

JCV/61/CO-cl infection of rhesus monkeys results in detectable viremia and a high level of neutralizing antibody

Virus titer on indicated day (log10 PFU/mL)a

Serum neutralizing antibody titer on day 28 as assayed against indicated virusb



Monkey #

2

4

JCV/61/CO-cl

JCV/03/CT-cl

JCV/04/CT-cl


A5E054

0.7

< 0.7

195

64

505

A5E060

< 0.7

< 0.7

253

72

464

A5E068

< 0.7

< 0.7

260

165

571

A5E069

2.2

< 0.7

181

97

201

A5E070

2.5

< 0.7

172

78

205

A5E073

2.5

2.0

166

73

195

A5E077

3.0

< 0.7

180

83

244

DBXG

1.9

1.9

62

18

78


GMTc:

171

71

259


a Serum was collected on days 0, 2, 4, 5, 8, 10, and 12. Virus was only detectable on days 2 and 4 with a lower limit of detection of 0.7 log10 PFU/mL.

b Reciprocal plaque reduction neutralization titer 60% (PRNT60).

c Geometric mean titer.

Bennett et al. Virology Journal 2011 8:136   doi:10.1186/1743-422X-8-136

Open Data