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Open Access Research

Antibody dependent enhancement of frog virus 3 infection

Heather E Eaton, Emily Penny and Craig R Brunetti*

Author Affiliations

Department of Biology, Trent University, Peterborough, ON, K9J 7B8, Canada

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Virology Journal 2010, 7:41  doi:10.1186/1743-422X-7-41

Published: 18 February 2010

Additional files

Additional file 1:

ADE occurs during an FV3 infection. ADE occurs during an FV3 infection in (A) BF-2 and (B) FHM cells. Original plaque numbers and standard error from three individual experiments are shown.

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Additional file 2:

Rabbit anti-FV3 serum neutralizes an FV3 infection in BGMK cells. Original plaque numbers and standard error from three individual experiments are shown.

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Additional file 3:

Addition of rabbit pre-immune serum to BF-2 cells inhibits ADE. Original plaque numbers and standard error from three individual experiments are shown.

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Additional file 4:

ADE in FV3 is Fc-dependent. Protein A incubated with either (A) anti-FV3 serum or (B) BF-2 cells abolished ADE in BF-2 cells. Original plaque numbers and standard error from three individual experiments are shown.

Format: XLS Size: 27KB Download file

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Additional file 5:

ADE in FV3 is complement independent. Treatment of anti-FV3 serum with (A) heat inactivation, (B) EGTA, and (C) zymosan A did not affect ADE. Original plaque numbers and standard error from three individual experiments are shown.

Format: XLS Size: 28KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data