Table 1 |
|
|
Contraindications situations for pegylated interferon and ribavirin therapy |
|
|
Contraindications levels |
Situations |
|
|
|
|
No more contraindications |
- Regular alanine aminotransferase |
|
- Methadone maintenance |
|
|
- Anemia/thrombocytopenia and neutropenia |
|
|
- Restricted seizure |
|
|
- Age more than 65 years |
|
|
- Excess use of alcohol |
|
|
|
|
|
Virtual contraindications |
- Depression |
|
- Psychosis |
|
|
- Autoimmune disorder |
|
|
- Drug abuser |
|
|
- Renal failure (with dialysis) |
|
|
|
|
|
Tough although not general contraindications |
-Alcohol use |
|
-Coronary artery disorder |
|
|
- Hepatic decompensation |
|
|
- Transplantation of solid organ (except liver) |
|
|
|
|
|
General contraindications |
- Pregnancy |
|
|
|
|
Munir et al. Virology Journal 2010 7:296 doi:10.1186/1743-422X-7-296 |
|
