Table 4 |
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|
EBV DNA load and antibody titre detection rates in the population samples (Group 5, n = 218). |
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|
Target |
Positive n (%) |
Detectable Range |
Spearman correlation (p) |
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|
|
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|
EBNA-1 DNA load |
BHRF-1 DNA load |
Combined EBV Targets DNA load |
VCA IgG |
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|
|
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|
EBV EBNA-1 DNA load (copies/ml) |
24 (11.0%) |
2.0 × 102 - 9.1 × 104 |
1.00 |
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|
EBV BHRF-1 DNA load (copies/ml) |
47 (21.6%) |
2.0 × 102 - 3.3 × 104 |
0.63 p < 0.001 |
1.00 |
||
|
Combined EBV targets DNA load (mean of BHRF & EBNA loads where both positive) (copies/ml) |
49 (22.5%) |
2.0 × 102 - 6.2 × 104 |
0.73 p < 0.001 |
0.97 p < 0.001 |
1.00 |
|
|
Viral capsid antigen IgG (titres) |
209 (95.9%) |
1:10 - 1:5120 |
0.11 p = 0.11 |
0.13 p = 0.05 |
0.14 p = 0.04 |
1.00 |
|
|
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|
Abbreviations: EBV, Epstein-barr virus; EBNA-1, Epstein-barr virus nuclear antigen-1; BHRF-1, BamHI fragment H rightward open reading frame-1; VCA, viral capsid antigen; IgG, immunoglobulin G; Pos, positive |
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|
Lay et al. Virology Journal 2010 7:252 doi:10.1186/1743-422X-7-252 |
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