Table 4

EBV DNA load and antibody titre detection rates in the population samples (Group 5, n = 218).

Target

Positive

n (%)

Detectable Range

Spearman correlation (p)


EBNA-1 DNA load

BHRF-1 DNA load

Combined EBV Targets DNA load

VCA IgG


EBV EBNA-1 DNA load

(copies/ml)

24 (11.0%)

2.0 × 102 - 9.1 × 104

1.00

EBV BHRF-1 DNA load

(copies/ml)

47 (21.6%)

2.0 × 102 - 3.3 × 104

0.63

p < 0.001

1.00

Combined EBV targets DNA load

(mean of BHRF & EBNA loads where both

positive) (copies/ml)

49 (22.5%)

2.0 × 102 - 6.2 × 104

0.73

p < 0.001

0.97

p < 0.001

1.00

Viral capsid antigen IgG

(titres)

209 (95.9%)

1:10 - 1:5120

0.11

p = 0.11

0.13

p = 0.05

0.14

p = 0.04

1.00


Abbreviations: EBV, Epstein-barr virus; EBNA-1, Epstein-barr virus nuclear antigen-1; BHRF-1, BamHI fragment H rightward open reading frame-1; VCA, viral capsid antigen; IgG, immunoglobulin G; Pos, positive

Lay et al. Virology Journal 2010 7:252   doi:10.1186/1743-422X-7-252

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