Effect of an integrase inhibitor on the formation of HDAC4 foci in infected cells. HeLa cells were infected with the HIV-1-based vector in the presence and absence of the integrase inhibitor (100 μM), or were treated only with the inhibitor, as indicated. Cells were processed as in Fig. 2, at 8 hrs post-infection. M - mock, uninfected cells, Inf - cells infected with the HIV-1-based vector, Inf+II - cells infected with the HIV-1-based vector and treated with the integrase inhibitor (added together with the virus), II - cells treated with the integrase inhibitor only. Other terminology as in Fig. 2.
Smith et al. Virology Journal 2010 7:237 doi:10.1186/1743-422X-7-237