The HDAC4 protein forms foci following infection with the HIV-1-based vector. HeLa cells were infected with an HIV-1-based vector as described in "Experimental Procedures". At indicated time points, samples were fixed and stained with the anti-HDAC4 antibody (top row). Nuclei were visualized using DAPI staining (middle row). Representative photographs are shown. DIC (differential interference contrast) shows the cell morphology (bottom row).
Smith et al. Virology Journal 2010 7:237 doi:10.1186/1743-422X-7-237