Research
Candidates in Astroviruses, Seadornaviruses, Cytorhabdoviruses and Coronaviruses for +1 frame overlapping genes accessed by leaky scanning
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Corresponding authors: Andrew E Firth A.Firth@ucc.ie - John F Atkins j.atkins@ucc.ie
1 BioSciences Institute, University College Cork, Cork, Ireland
2 Department of Human Genetics, University of Utah, Salt Lake City, UT 84112-5330, USA
Virology Journal 2010, 7:17 doi:10.1186/1743-422X-7-17
Published: 25 January 2010Abstract
Background
Overlapping genes are common in RNA viruses where they serve as a mechanism to optimize the coding potential of compact genomes. However, annotation of overlapping genes can be difficult using conventional gene-finding software. Recently we have been using a number of complementary approaches to systematically identify previously undetected overlapping genes in RNA virus genomes. In this article we gather together a number of promising candidate new overlapping genes that may be of interest to the community.
Results
Overlapping gene predictions are presented for the astroviruses, seadornaviruses, cytorhabdoviruses and coronaviruses (families Astroviridae, Reoviridae, Rhabdoviridae and Coronaviridae, respectively).