Table 1 |
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|
Overview HPV internalization studies |
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|
HPV type |
Methods |
Pathway |
Reference |
|
|
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|
HPV16 |
siRNA-mediated down regulation of clathrin heavy chain/caveolin-1/dynamin/tetraspanins dominant negative mutants of EPS15/caveolin-1/dynamin biochemical inhibitors caveolae-deficient cells |
clathrin- and caveolae-independent dynamin-independent lipid raft independent involvement of tetraspanins |
[58] |
|
HPV16 HPV31 |
biochemical inhibitors |
clathrin-dependent |
[66] |
|
HPV16 HPV31 |
dominant negative mutant of EPS15/caveolin-1/dynamin-2 biochemical inhibitors co-localization studies of HPV16 and HPV31 association study of HPV31 with detergent resistant microdomains |
HPV16 clathrin-dependent HPV31 caveolae-dependent |
[65] |
|
HPV16 |
co-localization with BPV-L1 VLPs |
clathrin-dependent |
[63] |
|
HPV16 HPV31 HPV58 |
biochemical inhibitors microscopic analysis |
HPV16/58 clathrin-dependent HPV31 caveolae-dependent |
[64] |
|
HPV33 |
biochemical inhibitors |
non-caveolae dependent HPV33 uptake |
[59] |
|
|
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Horvath et al. Virology Journal 2010 7:11 doi:10.1186/1743-422X-7-11 |
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