A. Genome organization of human klassevirus 1. Conserved picornaviral domains present in klassevirus are noted. Pyrosequencing contigs that align to Aichi virus by TBLASTX with an E-value of less than 10-6 covered more than 75% of the genome (light purple). Pyrosequncing contigs that align to the human klassevirus 1 genome by BLASTN with an E-value of less than 10-6 covered more than 95% of the full genome. B. Scanning nucleotide pairwise identity using a 100-bp window is depicted for Aichi virus, bovine kobuvirus, and porcine kobuvirus. C. Scanning amino acid pairwise identity using a 100-bp window versus Aichi virus.
Greninger et al. Virology Journal 2009 6:82 doi:10.1186/1743-422X-6-82