Virology Journal

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Antigenic presentation of heterologous epitopes engineered into the outer surface-exposed helix 4 loop region of human papillomavirus L1 capsomeres

Yoshihiko Murata*, Paula M Lightfoote, Robert C Rose and Edward E Walsh

Virology Journal 2009, 6:81 doi:10.1186/1743-422X-6-81

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Research article   Open Access

Efficient production of chimeric Human papillomavirus 16 L1 protein bearing the M2e influenza epitope in Nicotiana benthamiana plants

Slavica Matić, Riccardo Rinaldi, Vera Masenga, Emanuela Noris BMC Biotechnology 2011, 11:106 (15 November 2011)

Engineered Nicotiana benthamiana plants transiently express a chimeric antigen consisting of the Human papillomavirus 16 (HPV-16) L1 protein fused to the M2e influenza epitope, which can self-assemble into virus-like particles with immunogenic potential.