Table 4 |
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|
Selective pressure on different sites between human and avian influenza |
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|
Human |
Avian |
|||||
|
|
||||||
|
Gene |
Domaina |
Position |
dN/dSb |
P-value |
dN/dS |
P-value |
|
|
||||||
|
M1 |
115 |
0.07 |
0.0031 |
0.06 |
< 0.001 |
|
|
121 |
0.11 |
0.039 |
0.07 |
< 0.001 |
||
|
137 |
0.69 |
0.61 |
0.03 |
< 0.001 |
||
|
|
||||||
|
M2 |
ex |
11 |
infc |
0.017 |
inf |
< 0.001 |
|
ex |
16 |
6.18 |
0.021 |
5.06 |
0.044 |
|
|
ex |
20 |
Inf |
0.094 |
inf |
< 0.001 |
|
|
cy |
54 |
1.36 |
0.50 |
0.50 |
0.12 |
|
|
cy |
57 |
3.62 |
0.050 |
inf |
0.12 |
|
|
cy |
78 |
0.74 |
0.68 |
0.26 |
0.086 |
|
|
cy |
86 |
3.47 |
0.16 |
0.64 |
0.64 |
|
|
cy |
93 |
1.27 |
0.71 |
inf |
0.067 |
|
|
|
||||||
|
aEx indicates extracellular domain; Tr, transmembrane domain; and Cy, cytoplasmic domain. bdN/dS was calculated by eFEL. c"inf" means infinity as denominator is 0. Significance of the FEL test for positive selection levels is given as P-values, and underlined values indicate P-values for negative selection. Bold values are those deemed to indicate significantly positive or negative selection (P < 0.05). |
||||||
|
Furuse et al. Virology Journal 2009 6:67 doi:10.1186/1743-422X-6-67 |
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