Table 4 

Selective pressure on different sites between human and avian influenza 

Human 
Avian 



Gene 
Domain^{a} 
Position 
dN/dS^{b} 
Pvalue 
dN/dS 
Pvalue 


M1 
115 
0.07 

0.06 


121 
0.11 

0.07 


137 
0.69 
0.61 
0.03 




M2 
ex 
11 
inf^{c} 
0.017 
inf 
< 0.001 
ex 
16 
6.18 
0.021 
5.06 
0.044 

ex 
20 
Inf 
0.094 
inf 
< 0.001 

cy 
54 
1.36 
0.50 
0.50 


cy 
57 
3.62 
0.050 
inf 
0.12 

cy 
78 
0.74 

0.26 


cy 
86 
3.47 
0.16 
0.64 


cy 
93 
1.27 
0.71 
inf 
0.067 



^{a}Ex indicates extracellular domain; Tr, transmembrane domain; and Cy, cytoplasmic domain. ^{b}dN/dS was calculated by eFEL. ^{c}"inf" means infinity as denominator is 0. Significance of the FEL test for positive selection levels is given as Pvalues, and underlined values indicate Pvalues for negative selection. Bold values are those deemed to indicate significantly positive or negative selection (P < 0.05). 

Furuse et al. Virology Journal 2009 6:67 doi:10.1186/1743422X667 