Table 3 |
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|
Sites under positive selection for human influenza |
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|
Gene |
Domaina |
Position |
dN/dSb |
eSLAC |
iSLAC |
tSLAC |
eFEL |
iFEL |
|
|
||||||||
|
M1 |
219 |
infc |
0.0048 |
0.22 |
0.022 |
0.0032 |
0.013 |
|
|
|
||||||||
|
M2 |
Ex |
11 |
inf |
0.074 |
0.23 |
0.33 |
0.017 |
0.0055 |
|
Ex |
12 |
inf |
0.0068 |
0.32 |
0.022 |
0.0026 |
0.024 |
|
|
Ex |
13 |
inf |
0.020 |
0.55 |
0.036 |
0.0025 |
0.064 |
|
|
Ex |
14 |
inf |
0.069 |
0.37 |
0.19 |
0.019 |
0.025 |
|
|
Ex |
16 |
6.18 |
0.015 |
0.027 |
0.27 |
0.021 |
0.0017 |
|
|
Ex |
21 |
inf |
0.071 |
0.37 |
0.19 |
0.036 |
0.040 |
|
|
Ex |
23 |
inf |
0.052 |
0.27 |
0.19 |
0.037 |
0.024 |
|
|
Tm |
27 |
4.42 |
0.054 |
0.59 |
0.039 |
0.082 |
0.20 |
|
|
Cy |
57 |
3.62 |
0.21 |
0.16 |
0.57 |
0.050 |
0.024 |
|
|
Cy |
89 |
inf |
0.002 |
0.12 |
0.016 |
0.0023 |
0.0046 |
|
|
|
||||||||
|
The significance of SLAC and FEL results for positive selection levels are given as P-values. aEx indicates extracellular domain; Tr, transmembrane domain; and Cy, cytoplasmic domain. bdN/dS was calculated by eFEL. c"inf" means infinity as denominator is 0. Bold values are those deemed to show significantly positive selection (P < 0.05). |
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|
Furuse et al. Virology Journal 2009 6:67 doi:10.1186/1743-422X-6-67 |
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