Table 3

Sites under positive selection for human influenza

Gene

Domaina

Position

dN/dSb

eSLAC

iSLAC

tSLAC

eFEL

iFEL


M1

219

infc

0.0048

0.22

0.022

0.0032

0.013


M2

Ex

11

inf

0.074

0.23

0.33

0.017

0.0055

Ex

12

inf

0.0068

0.32

0.022

0.0026

0.024

Ex

13

inf

0.020

0.55

0.036

0.0025

0.064

Ex

14

inf

0.069

0.37

0.19

0.019

0.025

Ex

16

6.18

0.015

0.027

0.27

0.021

0.0017

Ex

21

inf

0.071

0.37

0.19

0.036

0.040

Ex

23

inf

0.052

0.27

0.19

0.037

0.024

Tm

27

4.42

0.054

0.59

0.039

0.082

0.20

Cy

57

3.62

0.21

0.16

0.57

0.050

0.024

Cy

89

inf

0.002

0.12

0.016

0.0023

0.0046


The significance of SLAC and FEL results for positive selection levels are given as P-values.

aEx indicates extracellular domain; Tr, transmembrane domain; and Cy, cytoplasmic domain.

bdN/dS was calculated by eFEL.

c"inf" means infinity as denominator is 0.

Bold values are those deemed to show significantly positive selection (P < 0.05).

Furuse et al. Virology Journal 2009 6:67   doi:10.1186/1743-422X-6-67

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