Additional file 2.

Conserve blocks from the multiple sequence alignment of PolB sequences from NCLDVs. The data provided shows the presence of conserved residues for exonuclease and polymerase activities in the HcDNAV PolB and its close homologs. Species abbreviation is followed by a database sequence identifier. Intein sequences were removed from the sequences prior to alignment. The alignment was generated by T-Coffee [40] and ClustalX [41]. AmEPV: Amsacta moorei entomopoxvirus 'L'; APMV: Acanthamoeba polyphaga mimivirus; ASFV: African swine fever virus; CeV: Chrysochromulina ericina virus; EhV: Emiliania huxleyi virus 86; EsV: Ectocarpus siliculosus virus 1; FsV: Feldmannia species virus; HaV: Heterosigma akashiwo virus 01; HcDNAV: Heterocapsa circularisquama DNA virus; HvAv: Heliothis virescens ascovirus 3e; IIV: Invertebrate iridescent virus 6; LCDV: Lymphocystis disease virus 1; OtV: Ostreococcus virus OsV5; PBCV: Paramecium bursaria Chlorella virus 1; PoV: Pyramimonas orientalis virus; VAR: Variola virus.

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Ogata et al. Virology Journal 2009 6:178   doi:10.1186/1743-422X-6-178