Table 7

The polymorphisms in Helical Domain III of Vpr (residues 54–77)

Residue

Residues in NL4-3 Vpr

Variant residue(s) noted in viruses of different clades

Number of variants


55

A

E, G, I, L, M, P, Q, R, S, T, V

11

56

G

E, R

2

57

V

A, L, M, W

4

58

E

A, G, I, K, L, M, Q, R, T, V

10

59

A

D, F, I, L, M, N, P, S, T, V

10

60

I

F, L, M, T, V, Y

6

61

I

A, L, M, T, V, Y

6

62

R

I, K, L, Q, S, T, W

7

63

I

F, L, M, S, T, V, Y

7

64

L

F, V

2

65

Q

H, R

2

66

Q

H, K, L, R

4

67

L

A, F, I, M, P, Q

6

68

L

I, M, P, R

4

69

F

L, S, V

3

70

I

A, T, V

3

71

H

L, Y

2

72

F

S, Y, L

3

73

R

G, S, T

3

74

I

F, H, L, M, N, S, T, V

8

75

G

K, R

2

76

C

G, S, Y

3

77

R

A, H, L, K, N, P, Q, S, T, W

10


Srinivasan et al. Virology Journal 2008 5:99   doi:10.1186/1743-422X-5-99

Open Data