Table 20

Effect of variant amino acids on CTL Epitope corresponding to residues 66–74 of Vpr

Amino Acid Sequence of Predicted Epitope

Scoreβ


Prototype sequence (start position 66)α

QLLFVHFRI

223.888

Natural variations observed at this epitope

HLLFVHFRI

7.612

KLLFVHFRI

783.608

LLLFVHFRI

380.609

RLLFVHFRI

223.888

QFLFVHFRI

0.155

QILFVHFRI

30.785

QMLFVHFRI

161.697

QPLFVHFRI

1.461

QQLFVHFRI

22.700

QLIFVHFRI

60.510

QLMFVHFRI

223.888

QLPFVHFRI

60.510

QLRFVHFRI

4.599

QLLFVLFRI

514.942

QLLFVYFRI

335.832

QLLFVHLRI

38.601

QLLFVHYRI

38.601

QLLFVHSRI

38.601

QLLFVHFRF

1.599

QLLFVHFRH

1.599

QLLFVHFRL

458.437

QLLFVHFRM

106.613

QLLFVHFRN

1.599

QLLFVHFRS

1.599

QLLFVHFRT

159.920

QLLFVHFRV

1,492.586


α Accession No.: A1.TZ.01.A341_AY253314

β Estimate of Half Time of Disassociation of a Molecule Containing This Epitope

Srinivasan et al. Virology Journal 2008 5:99   doi:10.1186/1743-422X-5-99

Open Data