Table 19

Effect of variant amino acids on CTL Epitope corresponding to residues 38–46 of Vpr

Amino Acid Sequence of Predicted Epitope

Scoreβ


Prototype sequence (start position 38)α

WLHELGQQI

196.763

Natural variations observed at this epitope

CLHELGQQI

42.774

FLHELGQQI

196.763

TLHELGQQI

42.774

YLHELGQQI

196.763

WFHELGQQI

0.137

WLIELGQQI

196.763

WLLELGQQI

728.022

WLMELGQQI

728.022

WLNELGQQI

196.763

WLQELGQQI

196.763

WLRELGQQI

14.954

WLTELGQQI

196.763

WLYELGQQI

629.64

WLHALGQQI

47.991

WLHDLGQQI

196.763

WLHGLGQQI

47.991

WLHHLGQQI

47.991

WLHNLGQQI

47.991

WLHQLGQQI

47.991

WLHRLGQQI

47.991

WLHSLGQQI

47.991

WLHWLGQQI

47.991

WLHECGQQI

196.763

WLHEFGQQI

747.698

WLHEIGQQI

196.763

WLHEMGQQI

196.763

WLHEVGQQI

196.763

WLHELGEQI

96.414

WLHELGHQI

196.763

WLHELGKQI

196.763

WLHELGLQI

196.763

WLHELGNQI

196.763

WLHELGRQI

39.353

WLHELGTQI

196.763

WLHELGVQI

196.763

WLHELGQFI

1082.194

WLHELGQHI

196.763

WLHELGQLI

196.763

WLHELGQWI

1082.194

WLHELGQYI

1082.194

WLHELGQQD

0.281

WLHELGQQV

1311.751


α Accession No.: A1.TZ.01.A341_AY253314

β Estimate of Half Time of Disassociation of a Molecule Containing This Epitope

Srinivasan et al. Virology Journal 2008 5:99   doi:10.1186/1743-422X-5-99

Open Data