Table 18

Effect of variant amino acids on CTL epitope corresponding to residues 18–26 of Vpr

Amino Acid Sequence of Predicted Epitope

Scoreβ


Prototype sequence (start position 18)α

WMLDLLEDL

1,213.356

Natural variations observed at this epitope

GMLDLLEDL

263.773

RMLDLLEDL

263.773

WALDLLEDL

23.334

WILDLLEDL

231.004

WLLDLLEDL

1,680.031

WPLDLLEDL

10.967

WRLDLLEDL

0.233

WSLDLLEDL

10.967

WVLDLLEDL

147.003

WTLDLLEDL

23.334

WMIDLLEDL

327.934

WMMDLLEDL

1,213.356

WMVDLLEDL

327.934

WMLALLEDL

295.940

WMLELLEDL

1,213.356

WMLGLLEDL

295.940

WMLKLLEDL

295.940

WMLTLLEDL

295.940

WMLDLSEDL

527.546

WMLDLVEDL

1,213.356

WMLDLLDDL

1,213.356

WMLDLLGDL

321.911

WMLDLLKDL

2,476.237

WMLDLLQDL

2,476.237

WMLDLLRDL

495.247

WMLDLLEDF

4.233

WMLDLLEDI

592.569


α Accession No.: A1.TZ.01.A341_AY253314

β Estimate of Half Time of Disassociation of a Molecule Containing This Epitope

Srinivasan et al. Virology Journal 2008 5:99   doi:10.1186/1743-422X-5-99

Open Data