Table 16

The extent of amino acid polymorphisms in experimentally defined CTL epitopes

Location of the epitope in Vpr

Amino acid sequence

Total number of variant amino acids in the CTL epitope

Reference


1 – 18

MEQAPENQGLQREPYNEW

87

[86]

9 – 26

GPQREPYNEWTLELLEEL

87

[87]

12 – 20

REPHNEWTL

53

[28,88,89]

19 – 28

TLEILEELKN

51

[86]

25 – 40

ELKNEAVRHFPRIWLH

87

[90]

29 – 37

EAVRHFPRI

52

[91-94]

30 – 38

AVRHFPRIW

52

[28,88,95]

31 – 50

VRHFPRWLHSLGQYIYETY

107

[96]

31 – 39

VRHFPRIWL

48

[97]

34 – 42

FPRIWLHGL

58

[28,87,89,97-103]

41 – 49

SLGQHIYET

49

[99]

41 – 57

GLGQYIYETYGDTWTGV

82

[87]

46 – 54

IYETYGDTW

36

[104]

48 – 57

ETYGDTWTGV

50

[87,97]

52 – 62

DTWAGVEAIIR

66

[97]

53 – 63

TWAVEAIIRI

69

[92]

55 – 70

AGVEAIIRILQQLLFI

86

[28]

59 – 67

AIIRILQQL

49

[10,28,89,96,98,105,106]

62 – 70

RILQQLLFI

38

[89,98,106]


Srinivasan et al. Virology Journal 2008 5:99   doi:10.1186/1743-422X-5-99

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