Table 14

The frequency of variant amino acids in Helical Domain III of Vpr (Residues 55–77)

Residue

Residues in NL4-3 Vpr

Variant residue(s) noted in viruses of subtype B


55

A

E (2.2), P (1.1), Q (0.4), T (19.6), V (1.8)

56

G

R (0.4), E (0.7)

57

V

W (0.4)

58

E

G (1.1), I (0.4), K (1.1), Q (0.7), V (0.4)

59

A

L (0.4), P (0.4), S (0.4), V (0.4)

60

I

L (16.4)

61

I

L (0.4), M (1.1), T (3.3), V (1.5)

62

R

K (0.7), L (0.4), S (0.4)

63

I

M (5.8), S (1.8), T (11.3), V (1.8)

64

L

no change

65

Q

H (0.4)

66

Q

no change

67

L

M (1.5), P(0.7)

68

L

M (1.5)

69

F

L (1.8)

70

I

T (2.9), V (1.1)

71

H

L (0.4), Y (0.4)

72

F

S (1.5), Y (0.4)

73

R

T (0.7)

74

I

L (0.4), M (0.4), V (0.4)

75

G

R (1.1)

76

C

G (1.1)

77

R

H (5.5), Q (42.5)


Srinivasan et al. Virology Journal 2008 5:99   doi:10.1186/1743-422X-5-99

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