Table 10

The frequency of variant amino acids in Helical Domain I of Vpr (Residues 17–33)

Residue

Residues in NL4-3 Vpr

Variant residue(s) noted in viruses of subtype B


17

E

A (3.3), D (0.4), G (0.4), Q (2.2), V (0.4)

18

W

no change

19

T

A (12.7), R (0.4)

20

L

I (4.4)

21

E

G (0.4)

22

L

F (0.4), I (1.1), P (0.4)

23

L

V (0.4), S (0.4)

24

E

G (0.4), K (0.4), Q (0.7), R (0.4)

25

E

A (0.4), D (2.9), K (0.4)

26

L

no change

27

K

N (0.4)

28

S

G (0.4), H (0.7), N (43.5), R (4.7), T (2.5)

29

E

D (0.4), V (0.4)

30

A

P (0.4)

31

V

A (0.4), D (0.4), I (0.4), L (0.4), T (0.4)

32

R

K (3.6), Q (0.4), W (0.4)

33

H

R (3.6)


Srinivasan et al. Virology Journal 2008 5:99   doi:10.1186/1743-422X-5-99

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