|
Activity of CDV Against Wild Type and CDV Resistant VV using a Plaque Reduction Assay in Human Foreskin Fibroblast and Vero Cells |
||||
| Virus |
HFF EC50 (μM)a |
Vero EC50 (μM)a |
Fold resistance over parental strain (HFF) |
Fold resistance over parental strain (Vero) |
|
|
||||
| VV-WR, UAB |
28 ± 4.4 |
62 ± 12 |
- |
- |
| VV-WR, Moyer |
18 ± 9.2 |
54 ± 2.9 |
- |
- |
| CDVR 1A |
122 ± 69 |
>317 ± 0 |
7 |
>6 |
| CDVR 15A |
98 ± 55 |
214 ± 17 |
5 |
4 |
| CDVR 16A |
49 ± 4.5 |
199 ± 2.8 |
3 |
4 |
|
aValues are the mean ± standard deviation of two or more assays. | ||||
Becker et al. Virology Journal 2008 5:58 doi:10.1186/1743-422X-5-58 |
||||