Figure 5.

Domains of E9 and locations of mutations responsible for drug resistance. The location of the putative exonuclease and polymerase domains is indicated. Mutations conferring resistance to CDV are indicated by circles. In addition to the location of known CDV mutations (circles), mutations conferring resistance to phosphonoacetic acid (closed triangles), cytosine arabinoside (open triangle) and aphidicolin (asterisk) are shown [17–19].