Figure 3.

Inhibition of the human and murine lymphotactin receptor by the viral antagonist vCCL2. Dose-response experiments for inhibition of IP₃-turnover by the antagonist vCCL2 induced by XCL1 (black square) mXCL1 (black triangle) and vCCL3 (white circle) in COS-7 cells transiently transfected with the human and murine lymphotactin receptors XCR1 and mXCR1 and the promiscuous chimeric G-protein Gqi4myr. All assays were performed in duplicate.