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Therapeutic immunisation of rabbits with cottontail rabbit papillomavirus (CRPV) virus-like particles (VLP) induces regression of established papillomas

Vandana A Govan email, Edward P Rybicki email and Anna-Lise Williamson email

Virology Journal 2008, 5:45doi:10.1186/1743-422X-5-45

Vaccination group different before vaccines started

Farrel Buchinsky   (07 May 2009)  Allegheny-Singer Research Institute email

The papilloma sizes in the two groups (control vs. cotton tail rabbit papillomavirus virus-like particles) clearly had a very different course as depicted in Figure 1. Why was there a difference between the groups one week before vaccination (week 7) and a more stark difference at the time of commencing the vaccine (week 8). Does the difference increase the chance of the overall result being a false positive?

How does this rabbit paper relate to a similar study that was done in dogs? Kuntsi-Vaattovaara H et al. Resolution of persistent oral...[PMID: 19379331]pubmed link

Competing interests

None declared

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