Phylogenetic tree analysis showing patient sequence purity. Phylogenetic analysis on the 305 HIV-1 env gp120 C2-V5 region sequences from plasma, peripheral blood mononuclear cells, CD4+ T cells, CD8+ T cells and monocytes. Using the ProML program of the PHYLIP software package, a maximum likelihood phylogenetic tree was calculated for our patient sequences. The branch lengths are scaled to distance. A single asterisk represents each sequence from our dataset. Individual sequences are not identified as it is only the broad pattern of clustering that is of interest here. Distinct clustering of patient-related sequences can be seen from the phylogenetic tree.
Ho et al. Virology Journal 2008 5:14 doi:10.1186/1743-422X-5-14