Table 2

Comparisons of serological markers for HBV replication versus HBVDNA copies in serum specimens.

HBV DNA+
 HBV DNA-
Sensitivity(%)
 Specificity(%)
 PPV(%)
 NPV (%)
 Overall (%)
HBpreSAg+
 48
 34
68
 56
 59
 66
 62
HBpreSAg-
 23
 44
 CI,95%
 55–78
 45–67


n = 149

HBV DNA+
 HBV DNA-
Sensitivity(%)
 Specificity(%)
 PPV(%)
 NPV (%)
 Overall (%)
HBeAg+
 43
 7
61
 91
 86
 72
 77
HBeAg-
 28
 71
 CI,95%
 48–72
 82-96


n=149

HBeAg+
 HBeAg-
Sensitivity(%)
 Specificity(%)
 PPV(%)
 NPV (%)
 Overall (%)
HBpreSAg+
 35
 49
70
 53
 42
 79
 58
HBpreSAg-
 15
 55
 CI,95%
 55-82
 43-63


n=154

Lian et al. Virology Journal 2007 4:93   doi:10.1186/1743-422X-4-93