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Subcellular localization prediction of vaccinia virus proteins |
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| Gene |
SwissProt Accession |
PSLT predictionsa |
Literature annotations |
Localization References |
Closest human homologueb |
BLAST e-value |
|
|
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| A34R |
P21057 |
PM |
Golgi |
[45] |
C-type lectin (NP_072092) |
0.02 |
| A38L |
P21061 |
PM |
PM |
[46] |
CD47 antigen (NP_001768) |
3E-22 |
| A39R |
P21062 |
Secreted and PM |
Secreted |
[47] |
semaphorin 7A (NP_003603) |
1E-30 |
| A40R |
P21063 |
PM |
PM |
[48] |
lectin-like receptor (NP_031359) |
2E-9 |
| B13R |
P20841 |
Secreted |
Cytoplasmic |
[49] |
plasminogen activator inhibitor-2 (NP_002566) |
5E-7 |
| B15R |
P21116 |
Secreted and PM |
PM or secreted |
[50] |
interleukin 1 receptor (NP_775465) |
4E-32 |
| B18R |
P21076 |
Cytosolic and nuclear |
Secreted and PM |
[51] |
Ankyrin 3 isoform 1 (NP_066267) |
1E-9 |
| B5R |
P21115 |
Secreted and PM |
PM and Golgi |
[45,52,53] |
coagulation factor XIII B (NP_001985) |
6E-17 |
| C12L |
P20531 |
Secreted |
Secreted |
[54] |
serine proteinase inhibitor (NP_002965) |
4E-47 |
| C2L |
P21037 |
Nuclear and cytosolic |
Cytoplasmic |
[55] |
kelch-like 10 (NP_689680) |
1e-024 |
| D8L |
P20508 |
PM |
PM |
[56] |
carbonic anhydrase XIII (NP_940986) |
8E-35 |
| A45R |
P21132 |
Cytosolic |
Cytoplasmic |
[3] |
superoxide dismutase 1 (NP_000445) |
3E-6 |
| D4R |
P20536 |
Nuclear and mitochondrial |
Cytoplasmic |
[56] |
- |
> 0.1 |
| D6R |
P20634 |
Nuclear |
Perinuclear |
[58] |
hypothetical protein (NP_060139) |
0.027 |
| E9L |
P20509 |
Nuclear |
Cytoplasmic |
[57] |
polymerase alpha (NP_058633) |
9E-19 |
| E3L |
P21081 |
Nuclear |
Nuclear |
[59] |
adenosine deaminase (NP_001102) |
4E-6 |
| F17R |
P68454 |
Cytosolic and nuclear |
Cytoplasmic |
[60] |
- |
> 0.1 |
| F4L |
P20493 |
Cytosolic |
Cytoplasmic |
[57] |
ribonucleotide reductase M2 (NP_001025) |
1E-143 |
| A56R |
P20978 |
PM |
PM |
[61] |
dentin matrix acidic phosphoprotein (NP_004398) |
0.015 |
| K1L |
P20632 |
Cytosolic and nuclear |
Cytoplasmic |
[62] |
ankyrin 2 (NP_001139) |
1E-9 |
| K2L |
P20532 |
Secreted |
Extracellularly associated with infected cell |
[63] |
plasminogen activator inhibitor-1 (NP_000593) |
3E-35 |
| M1L |
P20640 |
Cytosolic and nuclear |
Cytoplasmic |
[64] |
ankyrin 3 (NP_066267) |
4E-13 |
| C11R |
P20494 |
PM and secreted |
Secreted |
[65] |
epiregulin (NP_001423) |
2E-10 |
|
a In the case of multi-compartmental proteins (proteins that are predicted with high probability to be present in more than one compartment), the two most likely compartments were retained by PSLT. PM: plasma membrane. b The closest human homologue was determined by using BLAST [38] against the NCBI human RefSeq dataset. We do not report a homologue when the BLAST e-value exceeds 0.1. | ||||||
Scott et al. Virology Journal 2006 3:24 doi:10.1186/1743-422X-3-24 |
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