Virology Journal

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Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells

Courtney R Plumlee, Catherine A Lazaro, Nelson Fausto and Stephen J Polyak*

Virology Journal 2005, 2:89 doi:10.1186/1743-422X-2-89

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Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes

Maoyin Pang, Shashi Bala, Karen Kodys, Donna Catalano, Gyongyi Szabo BMC Immunology 2011, 12:55 (30 September 2011)

Abstract | Full text | PDF | PubMed | Editor’s summary

Acute and prolonged alcohol use has a profound inhibitory effect on Type I Interferon (IFN) induction regardless of intracellular or cell surface-derived danger signals and impairs Type I IFN responses to viral or bacterial pathogen-derived signals.

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Arbidol: a broad-spectrum antiviral that inhibits acute and chronic HCV infection

Yury S Boriskin, Eve-Isabelle Pécheur, Stephen J Polyak Virology Journal 2006, 3:56 (19 July 2006)

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