Human herpesvirus 8 – A novel human pathogen
University of Maryland Baltimore, School of Medicine, Department of Pathology, 725 West Lombard Street, Rm. S407, Baltimore, Maryland 21201, USA
Virology Journal 2005, 2:78 doi:10.1186/1743-422X-2-78Published: 2 September 2005
In 1994, Chang and Moore reported on the latest of the gammaherpesviruses to infect humans, human herpesvirus 8 (HHV-8) . This novel herpesvirus has and continues to present challenges to define its scope of involvement in human disease. In this review, aspects of HHV-8 infection are discussed, such as, the human immune response, viral pathogenesis and transmission, viral disease entities, and the virus's epidemiology with an emphasis on HHV-8 diagnostics.