Figure 1.

Structural alignment of EV-71 and CV-A16 3D RNA polymerase amino acid sequences. EV-71 subgenotype B3, B4 and CV-A16/G10 amino acid sequences were aligned against the poliovirus 1 Mahoney 3D RNA polymerase template sequences (PDB: 1RDR). Conserved residues are indicated as (●) and each domain are boxed and labeled. Residues shared by EV-71 B3 virus and CV-A16 were highlighted in grey and residues unique for EV-71 B3 virus were highlighted in pink.