Figure 1.

Viral replication, immunological and tissue injury kinetics following acute HCV and HBV infection. Data summated from Figure 1 [29] and modified to represent typical patients with chronic viral persistence. Note: a) High level HCV replication for 6–8 weeks prior to any immune responses, b) onset of humoral immune response well after down-regulation of viral replication [34], and c) transaminase peaks occurs ~ 2weeks later.