Table 1

Small interfering RNA
Name
 Virus
 Start Nucleotide
 Target Sequence
Cap
 WNV Lineage I
 312
 gaacaaacaaacagcgatgaa
Cap-Mut
 WNV Lineage I
 312
 gaagaaagaaagaccgatgaa
M2
 Influenza A M2
 18
 ggtcgaaacgcctatcagaaa
3110
 WNV Lineage I
 3110
 gggcagttctgggtgaagt
3317
 WNV Lineage I
 3317
 ctacggtcaccctgagtga
4119
 WNV Lineage I
 4119
 gaggagcaagtctgctatgc
4823
 WNV Lineage I
 4823
 gtgtcaaggaggatcgact
5039
 WNV Lineage I
 5039
 gacggtgatgtgattgggct
5497
 WNV Lineage I
 5497
 gcagcaagaggttacattt
6337
 WNV Lineage II
 6337
 gttgaagtcatcacgaagt
6349
 WNV Lineage I
 6349
 gtggaagtcatcacgaagc
6915
 WNV Lineage I
 6915
 caacgagatgggttggcta
7353
 WNV Lineage I
 7353
 gaagaacgctgtagtggat
7693
 WNV Lineage I
 7693
 ggacgcaccttgggagaggt
8892
 WNV Lineage I
 8892
 ggtcaacagcaatgcagct
8898
 WNV Lineage I
 8898
 cagcaatgcagctttgggt
9095
 WNV Lineage I
 9095
 gaagcagagccatttggtt
9607
 WNV Lineage I
 9607
 gggaaaggacccaaagtca
10355
 WNV Lineage I
 10355
 gagagatatgaagacacaac

siRNA were generated against 19–21 nucleotide sequences corresponding to the target region of different parts of the New York 1999 WNV genome. Sequences were chosen using the SciTools RNAi design program and compared against the GenBank database to exclude sequences that may affect cellular genes.

Geiss et al. Virology Journal 2005 2:53   doi:10.1186/1743-422X-2-53