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Summary of HCV transmission experiments with various hematopoetic and liver cells |
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| Short term |
Long term |
|
|
|
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| A. T-cells1 |
+ |
- |
| B. B-cells2 |
+ |
+ |
| C. Monocytes/macrophages3 |
+ |
- |
| D. Neuronal precursors4 |
+ |
+ |
| E. Liver cells5 |
||
| Kupffer's cells |
+ |
- |
| Hepatocyte |
+ |
+/- |
|
1T-cells isolated from human fetal chord blood. 2B-cells immortalized by infection with transforming EBV. 3Monocyte/Macrophages, adherent cells stimulated with PMA. 4Recently isolated neuronal cells from fetal human brain. 5Freshly isolated liver cells from liver biopsies. Kupffer's cells are liver macrophages and Hepatocytes are liver endothelial cells. | ||
Revie et al. Virology Journal 2005 2:37 doi:10.1186/1743-422X-2-37 |
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