Acanthamoeba polyphaga mimivirus and other giant viruses: an open field to outstanding discoveries
- Equal contributors
1 Universidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Laboratório de Vírus, Avenida Antônio Carlos, 6627, Caixa Postal 486, Bloco F4, Sala 258, 31270-901 Belo Horizonte, Minas Gerais, Brazil
2 URMITE, UM63, CNRS 7278, IRD 198, Inserm 1095, Aix Marseille Universite, Marseille, France
Virology Journal 2014, 11:120 doi:10.1186/1743-422X-11-120Published: 30 June 2014
In 2003, Acanthamoeba polyphaga mimivirus (APMV) was first described and began to impact researchers around the world, due to its structural and genetic complexity. This virus founded the family Mimiviridae. In recent years, several new giant viruses have been isolated from different environments and specimens. Giant virus research is in its initial phase and information that may arise in the coming years may change current conceptions of life, diversity and evolution. Thus, this review aims to condense the studies conducted so far about the features and peculiarities of APMV, from its discovery to its clinical relevance.