Induction of virus neutralizing antibodies by ChAdOx1-GnGc and HAdV5-GnGc vaccines. For each vaccination regimen the virus neutralizing response (VNT50), acquired as the antibody titer resulting in 50% reduction of plaque formation relative to cells incubated with RVF virus in the absence of mouse serum, is shown. The data represent medians (bars) and interquartile ranges (error bars) for 14 mice per regimen. The Mann–Whitney U test is used for statistical comparisons between regimens. ** p <0.01, NS – not significant.
Warimwe et al. Virology Journal 2013 10:349 doi:10.1186/1743-422X-10-349