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Immunogenicity and efficacy of a chimpanzee adenovirus-vectored Rift Valley Fever vaccine in mice

George M Warimwe1*, Gema Lorenzo2, Elena Lopez-Gil2, Arturo Reyes-Sandoval1, Matthew G Cottingham1, Alexandra J Spencer1, Katharine A Collins1, Matthew DJ Dicks1, Anita Milicic1, Amar Lall1, Julie Furze1, Alison V Turner1, Adrian VS Hill1, Alejandro Brun2 and Sarah C Gilbert1

Author Affiliations

1 The Jenner Institute, University of Oxford, Oxford, UK

2 Centro de Investigación en Sanidad Animal, Instituto Nacional de Investigación Agraria y Alimentaria, Valdeolmos, Madrid, Spain

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Virology Journal 2013, 10:349  doi:10.1186/1743-422X-10-349

Published: 5 December 2013

Additional files

Additional file 1: Figure S1:

Vaccine design and confirmation of transgene expression. Figure S2. Cytokine profiling of vaccine-induced CD8+ T cells. Figure S3. IFNγ ELISpot responses at eight weeks post-vaccination. Table S1. Software prediction of epitopes within immunodominant peptides.

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