Percentages of Natural Killer (NK) cells and their subsets; lytic potential of NK cells. A: Representative dot plot of CD16lowCD56bright; CD16+CD56bright, CD16+, CD56dim and CD16brightCD56- cells. Based on forward and side scatter analysis, cells were first gated on lymphocytes (not shown) and then on CD3- cells. B: Absolute numbers of CD4+ T-cells (light grey line, number of CD4/mm3), % of CD56bright in total CD56 NK cells (dark grey line, % of CD56bright cells) and HIV viral load (black line, number of copies/mL) during one year. C: Representative dot plots of the expression of activating and inhibitory receptors on NK-cells among CD56+ CD16+/− cells. D: Representative dot plots of CD107a degranulation and IFN-γ secretion on CD56dim and CD56bright cells, following PBMC activation by K562.
Fregni et al. Virology Journal 2013 10:33 doi:10.1186/1743-422X-10-33