Figure 4.

Effect of TSA or coexpression of p300 on JCV transcription in TC620 cells expressing NF-κB p65. A. TC620 cells were transfected with the reporter plasmid JCVL-LUC and NF-κB p65 expression plasmid and treated with TSA as indicted, harvested and assayed for luciferase activity. B. TC620 cells were transfected with the reporter plasmid JCVE-LUC (EARLY) or JCVL-LUC (LATE) and expression plasmid for p300 as indicated, harvested and assayed for luciferase activity. C. TC620 cells were transfected with the reporter plasmid JCVE-LUC or JCVL-LUC and expression plasmids for p65 and p300 as indicated, harvested and assayed for luciferase activity. Activities were normalized to untreated controls. The bar represents one standard deviation.

Wollebo et al. Virology Journal 2013 10:264   doi:10.1186/1743-422X-10-264
Download authors' original image