Phylogenetic analysis using VP1 gene sequences (855 bp) of EV71. The tree was constructed using ML method, with bootstrap values calculated from 1000 trees. Black circles and squares indicate EV71 isolates of subgenotype C4 (proposed genotype D) and those of subgenotype C2 respectively from Hong Kong in the present study. A vertical black line indicates a potential distinct lineage of EV71 subgenotype C2 strains.
Yip et al. Virology Journal 2013 10:222 doi:10.1186/1743-422X-10-222