Immunofluorescent assays of microglia (with Iba-1 specific antibody) and PrPSc (with PrP specific antibody) in the temporal lobes of different human prion diseases. The images of PrPSc (green), Iba-1 (red), DAPI (blue) and merge are monitored under a confocal microscopy and indicated above. Various prion diseases and normal control are indicated on the left.
Shi et al. Virology Journal 2013 10:216 doi:10.1186/1743-422X-10-216