Table 2

Clinical presentations of patients acquiring CVA6 and non-CVA6 enterovirus infection
CVA6 positive (N=81) Non-CVA6* (N=20) P value
Demographics
Age (year) 3.5 (±3.2) 2.8 (±1.5) 0.92
Male 54 (67%) 11 (55%) 0.33
Female 27 (33%) 9 (45%)
Sites
Limbs 80 (99%) 18 (90%) 0.10
  Arm/Leg/Thigh 56 (69%) 16 (80%) 0.79
Trunk 22 (27%) 7 (35%) 0.58
Buttocks 25 (30%) 6 (30%) 1.00
Face 34 (41%) 8 (40%) 0.80
  Ear lobes 11 (13%) 0 0.12
  Perioral area 23 (28%) 4 (20%) 0.27
Morphology
Large vesicles 45 (56%) 5 (25%) 0.02
Symptoms
Fever 66 (80%) 15 (75%) 0.37
Sore throat 49 (60%) 10 (50%) 0.45
Cough/rhinorrhea 23 (28%) 7 (35%) 0.58
Vomit/diarrhea 11 (13%) 6 (30%) 0.10
Skin lesions
  Itchiness 27 (33%) 5 (25%) 0.60
  Pigmentation 6 (7%) 3 (15%) 0.34
  Prickle 2 (2%) 0 (0%) 1.00
Myoclonic jerks 11 (13%) 3 (15%) 1.00
Hospitalization
Days (days) 3.4 (± 1.3) 2.3 (± 0.6) 0.24
Age (years) 2.3 (± 3.1) 2.3 (± 0.6) 0.30

CVA6 denotes coxsackievirus A6.

* including 6 of CVA16, 1 of EV71, 1 of CVA5 and 12 of non-typable enterovirus.

Huang et al.

Huang et al. Virology Journal 2013 10:209   doi:10.1186/1743-422X-10-209

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