Table 1

Clinical presentations of two types of atypical HFMD
A typical HFMD (N=101) Large vesicles (N=50) Small rashes (N=51) P value*
Demographics
Age (year) 3.3 (± 3.8) 4.0 (± 3.7) 2.7 (± 1.8) 0.12
Male 65 (64%) 35 (70%) 30 (59%) 0.004
Female 36 (36%) 15 (30%) 21 (41%)
Etiology
  CVA6 81 (80%) 45 (90%) 36 (70%) 0.01
Sites
Limbs 98 (97%) 49 (98%) 49 (96%) 1.00
  Arm/Leg/Thigh 71 (70%) 35 (70%) 36 (70%) 1.00
Trunk 29 (29%) 21(42%) 8 (16%) 0.004
Buttocks 31 (31%) 17 (34%) 14 (27%) 0.52
Face 40 (41%) 22 (44%) 18 (35%) 0.42
  Ear lobes 11 (11%) 6 (12%) 5 (10%) 0.76
  Perioral area 26 (26%) 16 (32%) 10 (20%) 0.18
Symptoms
Fever 80 (80%) 40 (80%) 39 (76%) 0.81
Sore throat 59 (58%) 33 (66%) 26 (51%) 0.16
Cough/rhinorrhea 27 (27%) 14 (28%) 13 (25%) 0.83
Vomit/diarrhea 17 (17%) 6 (12%) 11 (22%) 0.29
Skin lesions
  Itchiness 32 (32%) 22 (44%) 10 (20%) 0.01
  Desquamation 1 (1%) 1 (2%) 0 (0%) 0.50
  Pigmentation 6 (9%) 5 (10%) 1 (2%) 0.11
  Prickle 2 (2%) 2 (4%) 0 (0%) 0.24
Myoclonic jerks 14 (14%) 5 (10%) 9 (18%) 0.39
Myalgia 2 (2%) 2 (4%) 0 (0%) 0.24

* P value represents the comparison of total numbers between male and female.

Huang et al.

Huang et al. Virology Journal 2013 10:209   doi:10.1186/1743-422X-10-209

Open Data