CD8+ T cell depletion. Animals vaccinated with Con M Envgp140 were all depleted of CD8+ cells by administering the M-T807R1 antibody subcutaneously (50 mg/Kg) at day 0 (day 70 post challenge). A) Number of CD8+ cells following antibody administration over the 25 day period of observation. B) Viral titers for each individual monkey are displayed as RNA copies/ml of blood on the y-axis by days post challenge on the x-axis.
Eugene et al. Virology Journal 2013 10:102 doi:10.1186/1743-422X-10-102