|
Histologic lesions of CDV-infected raccoons. |
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| Raccoon |
Sex |
M/Ya |
Siteb |
Presentation |
Encephalitisf |
Pneumoniah |
Other findings |
EMCVk |
|
|
||||||||
| 98-2645 |
F |
8/98 |
FPc |
Euthanized |
++; Demyelination; axonal loss; few IBg |
+++; Chronic; no IB |
Lymphoid depletion (LNi); IB – other sites |
- |
| 98-2646 |
M |
8/98 |
ZGd |
Dead |
- |
++; Sub-acute to chronic; no IB |
IB – other sitesj |
- |
| 98-2654 |
M |
10/98 |
ZG |
Euthanized |
Rare axonal loss |
++ |
Ocular discharge; CDV in footpad ("Hardpad" disease); lymphoid depletion (LN and spleen) |
- |
| 98-2655 |
F |
10/98 |
ZG |
Dead |
++; IB common |
None |
Lymphoid depletion (LN and spleen); IB – other sites |
- |
| 98-2666 |
F |
12/98 |
ZG |
Euthanized |
++; Axonal loss; rare neuronal IB |
++; Chronic; no IB |
Lymphoid depletion (LN and spleen); IB – other sites |
- |
| 00-2601 |
M |
1/00 |
ZG |
Euthanized |
++; Rare neuronal IB; severe axonal loss |
None |
IB – other sites |
- |
| 01-2641 |
M |
5/01 |
OFPe |
Euthanized |
+; IB; syncytia in hippocampus |
+++ with syncytia; IB |
Lymphoid depletion (LN and spleen); IB – other sites |
+ brain, LN, spleen) |
| 01-2663 |
F |
6/01 |
ZG |
Euthanized |
None |
+++ with syncytia; IB |
Lymphoid depletion (LN and spleen); IB – other sites |
- |
| 01-2676 |
F |
7/01 |
ZG |
Euthanized |
+; Axonal loss; neuronal necrosis; IB; syncytia in hippocampus |
+++; IB |
Lymphoid depletion (LN); IB – other sites |
- |
| 01-2689 |
F |
8/01 |
ZG |
Euthanized |
+; IB |
++ with syncytia; IB |
Lymphoid depletion (LN and spleen); IB – other sites; rhinitis; purulent conjunctivitis |
- |
| 01-2690 |
M |
8/01 |
ZG |
Euthanized |
Rare neuronal necrosis; IB |
None |
Lymphoid depletion (LN); IB – other sites |
+ (spleen) |
|
aM/Y; Month and year animal examined by necropsy and specimens frozen. bSite; Location where animal was trapped or found dead. cFP; Forest preserve at border of zoo. dZG; Zoo grounds. eOFP; Off-site forest preserve fEncephalitis: -, none; +, mild; ++, moderate. gIB; Characteristic intracytoplasmic or intranuclear inclusion bodies formed by Canine distemper virus. hPneumonia: +, mild; ++, moderate; +++, severe. iLN; Lymph node. JIB – other sites: Inclusion bodies in other epithelial sites. kEMCV, Encephalomyocarditis virus. | ||||||||
Lednicky et al. Virology Journal 2004 1:2 doi:10.1186/1743-422X-1-2 |
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